Article ID Journal Published Year Pages File Type
4272165 The Journal of Sexual Medicine 2009 13 Pages PDF
Abstract
At least two VDCC are expressed in rabbit corpus cavernousum myocytes. One may be designated L‐type Ca2+ current, whereas the other is a putative T‐type current. The L‐current facilitates conversion of local Ca2+ events into global Ca2+ waves, whereas the putative T‐current plays little part in this process. These results provide a new basis for understanding the role of L‐type Ca2+ current in generating detumescent tone in the corpus cavernosum. McCloskey C, Cagney V, Large R, Hollywood M, Sergeant G, McHale N, and Thornbury K. Voltage‐dependent Ca2+ currents contribute to spontaneous Ca2+ waves in rabbit corpus cavernosum myocytes.
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