| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4272270 | The Journal of Sexual Medicine | 2010 | 11 Pages |
Abstract
Systemic administration of flibanserin to female rats differentially affects the monoamine systems of the brain. This may be the mechanistic underpinning of flibanserin's therapeutic efficacy in HSDD, as sexual behavior is controlled by an intricate interplay between stimulatory (catecholaminergic) and inhibitory (serotonergic) systems. Allers KA, Dremencov E, Ceci A, Flik G, Ferger B, Cremers TIFH, Ittrich C, and Sommer B. Acute and repeated flibanserin administration in female rats modulates monoamines differentially across brain areas: A microdialysis study.
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Authors
Kelly A. PhD, Eliyahu PhD, Angelo PhD, Gunnar PharmD, Boris PhD, Thomas I.F.H. PhD, Carina PhD, Bernd PhD,