| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4272680 | The Journal of Sexual Medicine | 2008 | 13 Pages |
Abstract
These data suggest that AS702224 is a potent DP1-selective agonist that causes penile erection. The DP1 receptor mediates relaxation in human cavernosal tissue, and stimulates pro-erectile responses in rat and rabbit. Thus, rabbits and rats can be useful models for investigating the physiological function of DP1 receptors. Brugger N, Kim NN, Araldi GL, Traish AM, and Palmer SS. Pharmacological and functional characterization of novel EP and DP receptor agonists: DP1 receptor mediates penile erection in multiple species.
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Authors
Nadia PhD, Noel N. PhD, Gian Luca PhD, Abdulmaged M. PhD, Stephen S. PhD,