Expression and Distribution of Cyclic GMP-Dependent Protein Kinase-1 Isoforms in Human Penile Erectile Tissue

Our results demonstrate, for the first time, the expression of both cGKI α and β isoforms in the smooth musculature of HCA and HCC. Corresponding to recent findings from animal studies, the presence of cGKI α and β provides further evidence for a significant role of these enzymes in the control of smooth muscle function in human penile erectile tissue. Waldkirch E, Uckert S, Sigl K, Imkamp F, Langnaese K, Richter K, Jonas U, Sohn M, Stief C, Wolf G, and Hedlund P. Expression and distribution of cyclic GMP-dependent protein kinase-1 isoforms in human penile erectile tissue