Article ID Journal Published Year Pages File Type
4272750 The Journal of Sexual Medicine 2010 10 Pages PDF
Abstract
The present study showed that chronic sildenafil produced sustained vascular antioxidant effects in insulin-resistant rats by increasing NO release and regulating vascular superoxide release, supporting therefore further investigations using chronic sildenafil administration in preventing cardiovascular alterations associated with oxidative stress. Oudot A, Behr-Roussel D, Le Coz O, Poirier S, Bernabe J, Alexandre L, and Giuliano F. How does chronic sildenafil prevent vascular oxidative stress in insulin-resistant rats? J Sex Med 2010;7:79-88.
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