Nanoparticles as a Novel Delivery Vehicle for Therapeutics Targeting Erectile Dysfunction

Nanoparticles encapsulating three different erectogenic agents resulted in increased erectile function when applied to the penis of a rat model of ED. Nanoparticles represent a potential novel route for topical delivery of erectogenic agents which could improve the safety profile for existing orally administered drugs by avoiding effects of absorption and first-pass metabolism, and would be less hazardous than injection. Han G, Tar M, Kuppam DSR, Friedman A, Melman A, Friedman J, and Davies KP. Nanoparticles as a novel delivery vehicle for therapeutics targeting erectile dysfunction.