| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4273279 | The Journal of Sexual Medicine | 2007 | 11 Pages |
Abstract
pSilencer2.1-U6-PIN-shRNA gene therapy was more effective than the antisense PIN mRNA in ameliorating ED in the aged rat, thereby suggesting that PIN is indeed a physiological inhibitor of nNOS and nitrergic neurotransmission in the penis. Magee TR, Kovanecz I, Davila HH, Ferrini MG, Cantini L, Vernet D, Zuniga FI, Rajfer J, and Gonzalez-Cadavid NF. Antisense and short hairpin RNA (shRNA) constructs targeting PIN (protein inhibitor of NOS) ameliorate aging-related erectile dysfunction in the rat.
Keywords
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Authors
Thomas R. PhD, Istvan PhD, Hugo H. MD, Monica G. PhD, Liliana PhD, Dolores PhD, Freddi I. MSc, Jacob MD, Nestor F. PhD,