| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4273322 | The Journal of Sexual Medicine | 2006 | 5 Pages |
Abstract
Acidic pH may decrease the binding affinity of adrenergic ligands to their receptors. Phenylephrine at doses higher than previously reported may be necessary to overcome this decreased affinity in acidosis associated with ischemic priapism. Highâdose intracavernosal phenylephrine administration is safe and effective in the management of ischemic priapism. Continuous cardiovascular monitoring is advised. Wen CC, Munarriz R, McAuley I, Goldstein I, Traish A, and Kim N. Management of ischemic priapism with highâdose intracavernosal phenylephrine: from bench to bedside. J Sex Med 2006;3:918-922.
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Authors
C. Charles MD, Ricardo MD, Iain MD, FRCSC, Irwin MD, Abdulmaged PhD, Noel PhD,