Transrectal Saturation Biopsy Improves Risk Stratification (Reclassification) of Patients with Prostate Cancer on Active Surveillance

Disease progression or recategorization was more frequently identified on the first confirmatory biopsy than on subsequent surveillance biopsies. The incidence of disease recategorization was higher in the saturation biopsy group than in the extended biopsy group on the first confirmatory biopsy but the difference was not statistically significant. Disease progression was more likely to be identified by saturation prostate biopsy on subsequent surveillance biopsies.