Survival after surgery for hepatocellular carcinoma in relation to presence or absence of viral infection

BackgroundThe aim of this study was to compare postoperative survival between hepatocellular carcinoma (HCC) patients with and without viral infection.MethodsFrom among 398 HCC patients in our collected database, 377 who underwent surgery were enrolled. The patients were divided into 2 groups: group 1, those who had no hepatitis B virus or hepatitis C virus infection, and group 2, those who had hepatitis B virus or hepatitis C virus infection. Univariate analysis was performed to compare clinical factors, including viral infection, with overall survival. Kaplan-Meier analysis and the log-rank test were used to evaluate the overall and disease-free survival curves for the 2 groups.ResultsUnivariate analysis showed that viral infection showed no such association. Moreover, Kaplan-Meier analysis and the log-rank test revealed no significant intergroup differences in either overall or disease-free survival.ConclusionsThe presence or absence of viral infection shows no significant association with the postoperative survival of patients undergoing surgery for HCC.