| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4281729 | The American Journal of Surgery | 2006 | 6 Pages |
BackgroundIntestinal electrical stimulation (IES) with long pulses has been reported to inhibit motility as well as accelerate transit of continuous infusion. However, it is unknown whether there is a correlation between the IES-induced alterations in motility and transit and whether there is a difference in transit during IES between continuous infusion and bolus infusion.MethodsThe study was performed in 2 postprandial sessions (control and stimulation) in dogs with 2 pairs of serosal electrodes and 2 intestinal cannulas. Intestinal motility and transit with and without IES were measured by manometry and phenol red, respectively.ResultsIES significantly decreased intestinal motility and increased transit time. There was a significant correlation between motility index and transit during IES.ConclusionsIES inhibits both intestinal bolus motility and transit. There is correlation between motility and transit during IES.
