Pediatric aggressive giant cell granuloma of nasal cavity

•We learned a significant lesson about diagnosis & treatment through very interesting experience in the aggressive change after the first surgery.•We have to consider complete resection of indefinite GCG as a means of the high priority, despite younger age.•Pediatric aggressive GCG is the first published a pediatric case of GCG occurring in the nasal cavity with intracranial invasion.

IntroductionGiant cell granuloma (GCG) is a non-neoplastic osseous proliferative lesion of unknown etiology. Although a benign disease process, GCG can be locally destructive. It is extremely rare to have a pediatric case of GCG occurring in the nasal cavity with intracranial invasion.Presentation of caseWe report a case of an aggressive and recurrent giant cell granuloma with intracranial invasion in a 10 years old female patient which was completely excised with endoscopic craniofacial resection.DiscussionA literature review on pathogenesis, diagnosis and management is also performed.ConclusionThe most common treatment for giant cell granuloma is surgery, ranging from simple curettage to resection. However, it must be completely excised in cases of aggressive and extensive lesion because of the high recurrence rate after incomplete removal.