Article ID Journal Published Year Pages File Type
4289598 International Journal of Surgery Case Reports 2013 4 Pages PDF
Abstract

INTRODUCTIONBleeding related to low-molecular-weight heparins (LMWHs) is typically described as an excess of minor bleeding; however, several reports of spontaneous major bleeding have been noted.PRESENTATION OF CASEA 58-year-old female presented to the hospital with bilateral spontaneous lower extremity hematomas which rapidly enlarged. CT studies demonstrated active arterial extravasation from small vessels at multiple sites within each leg with no dominant feeding artery identified on either side. She required multiple transfusions, administration of protamine, fresh frozen plasma (FFP), recombinant activated Factor VII and eventual surgery.DISCUSSIONDalteparin provides an effective and economical method of anticoagulation, however there is a risk of significant, spontaneous arterial hemorrhage even in the absence of risk factors.CONCLUSIONDalteparin can cause major spontaneous bleeding from multiple arterial sources.

Related Topics
Health Sciences Medicine and Dentistry Surgery
Authors
, , ,