Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4293255 | Journal of the American College of Surgeons | 2012 | 14 Pages |
Abstract
The MAPK (mitogen-activated protein kinase)/ERK pathway is an important modulator of MMPs during AAA formation. Targeting the ERK pathway by reagents that inhibit either the expression or phosphorylation of ERK isoforms could be a potential therapy to prevent AAA formation.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Surgery
Authors
Abhijit PhD, Paul D. MD, Lauren K. MD, Omar BS, Brendan BS, John S. BS, Peter K. MD, FACS, Jonathan L. MD, FACS, Gilbert R. MD, FACS,