Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4305013 | Journal of Surgical Research | 2006 | 5 Pages |
Abstract
MMF weakens the integrity of colonic anastomosis, and this effect is more significant during the inflammatory phase of healing. MMF has a negative effect on macrophages and TGF-β1 expression, resulting in decreased collagen accumulation at the anastomosis.
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Authors
Nicholas M.D., Ph.D, F.R.C.S (Ed), George M.D., Ph.D, Dimitrios M.D., Ph.D, Dimitrios M.D., Vasilios M.D., Ph.D.,