Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4308811 | Surgery | 2011 | 15 Pages |
Abstract
Our data demonstrate a previously unknown involvement of the angiotensin II type 2 receptor in pancreatic ductal adenocarcinoma cell fatty acid synthesis and suggest that its blockade has potential as a novel chemopreventive and antilipogenic mechanism for human pancreatic ductal adenocarcinoma through the activation of AMP-activated protein kinase, which could have detrimental effects on cancer cell survival.
Related Topics
Health Sciences
Medicine and Dentistry
Surgery
Authors
Amy BS, Maheshwaran MD, Qiaoke MD, SuhYueh MD, Galina PhD, Charles J. MD, Hwyda A. MD, PhD,