Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4310100 | Surgery | 2008 | 10 Pages |
Abstract
p21 controls the intensity of the immune response posttransplantation, with overexpression inhibiting allograft rejection. Our data demonstrate that p21 controls T-cell priming and suggest that p21 and other cdk inhibitors may serve as potential targets for therapeutic manipulation of alloimmune responses.
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Authors
Theodore H. MD, Guanyi MD, Keri PhD, Sherri C. BS, Lamis PhD, D. Keith PhD,