Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4312866 | Behavioural Brain Research | 2013 | 5 Pages |
The present investigation aimed at evaluating the effects of long-term exposure to WIFI type radiofrequency (RF) signals (2.40 GHz), two hours per day during one month at a Specific Absorption Rate (SAR) of 1.60 W/kg. The effects of RF exposure were studied on wildtype mice and triple transgenic mice (3xTg-AD) destined to develop Alzheimer's-like cognitive impairment. Mice were divided into four groups: two sham groups (WT, TG; n = 7) and two exposed groups (WTS, TGS; n = 7). The cognitive interference task used in this study was designed from an analogous human cognitive interference task including the Flex field activity system test, the two-compartment box test and the Barnes maze test. Our data demonstrate for the first time that RF improves cognitive behavior of 3xTg-AD mice. We conclude that RF exposure may represent an effective memory-enhancing approach in Alzheimer's disease.
► Transgenic mice becomes less anxious: reduction of latency time. ► Not affected the locomotor activity. ► Correction of the spatial memory.