Article ID Journal Published Year Pages File Type
4313231 Behavioural Brain Research 2012 7 Pages PDF
Abstract

Neurogenesis occurs in the adult mammalian brain in discrete regions related to olfactory sensory signaling and integration. The olfactory receptor cell population is in constant turn-over through local progenitor cells. Also, newborn neurons are added to the olfactory bulbs through a major migratory route from the subventricular zone, the rostral migratory stream. The olfactory bulbs project to different brain structures, including: piriform cortex, amygdala, entorhinal cortex, striatum and hippocampus. These structures play important roles in odor identification, feeding behavior, social interactions, reproductive behavior, behavioral reinforcement, emotional responses, learning and memory. In all of these regions neurogenesis has been described in normal and in manipulated mammalian brain. These data are reviewed in the context of a sensory-behavioral hypothesis on adult neurogenesis that olfactory input modulates neurogenesis in many different regions of the brain.

► Neurogenesis occurs in regions related to the olfactory system. ► Newborn neurons are added to the olfactory system through different ways. ► Olfactory inputs modulates neurogenesis in different brain regions.

Related Topics
Life Sciences Neuroscience Behavioral Neuroscience
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