| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4313679 | Behavioural Brain Research | 2011 | 8 Pages |
Abstract
⺠Acute administration of AM receptor antagonist AM22-52 resumed potency of morphine. ⺠The AM22-52 treatment suppressed morphine tolerance-associated hyperalgesia. ⺠AM22-52 reversed morphine induced-enhancement of nNOS and CGRP in spinal dorsal horn and dorsal root ganglia. ⺠The first study to show association of endogenous opioid peptide with morphine potency.
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Authors
Dongmei Wang, Peiwen Chen, Qi Li, Rémi Quirion, Yanguo Hong,