Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4313823 | Behavioural Brain Research | 2011 | 5 Pages |
Abstract
The anterior cingulate cortex (ACC) and opioid receptors have been suggested to play a role in attributing incentive motivational properties to drug-related cues. We examined whether blockade of ACC opioid receptors would reduce cue-induced ethanol-seeking behavior in mice. We show that intra-ACC opioid receptor blockade disrupted expression of an ethanol-induced conditioned place preference, suggesting that endogenous opioid modulation in the ACC may be critical for maintaining the cue's conditioned rewarding effects.
Keywords
Related Topics
Life Sciences
Neuroscience
Behavioral Neuroscience
Authors
Christina M. Gremel, Emily A. Young, Christopher L. Cunningham,