Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4314061 | Behavioural Brain Research | 2010 | 4 Pages |
Abstract
We investigated the effects of bilateral infusions in the prelimbic cortex of d-cycloserine (DCS), a partial agonist of the NMDA receptor-associated glycine site. Wistar rats underwent a training session (acquisition, three trials) and a 24-h test (two retention and two relearning trials) of a rapidly learned olfactory discrimination task. Rats infused with DCS (10 μg/site) prior to training exhibited a significant enhancement of performance in such odor-reward task, especially in relearning.
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Authors
Irene Villarejo-Rodríguez, Anna Vale-Martínez, Gemma Guillazo-Blanch, Margarita Martí-Nicolovius,