An animal model of hypnotic pain attenuation

All animals in the normal group showed the greatest amount of pain conditioning, with an average disruption time (dt) of 175 s. Animals in the lidocaine group showed little signs of conditioning with an average dt of 16 s. Animals conditioned during TIS had an average dt of 42 s. These results show that TIS can modulate pain perception similar to animals that did not experience a pain CS. They additionally argue that tonic immobility can produce attenuation of pain perception similar to hypnosis in humans.