| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4314885 | Behavioural Brain Research | 2009 | 5 Pages |
Abstract
Intra-nucleus accumbens (Acb) infusion of cholinergic muscarinic antagonist, scopolamine (10 μg/0.5 μl), markedly reduced fat intake elicited by intra-Acb treatment of the μ-opioid receptor agonist, DAMGO, with 30 min and 4 h pretreatment intervals. Intra-Acb scopolamine infusions also reduced food intake in food-deprived rats, but not water intake in water-deprived rats. Hence, Acb muscarinic manipulations exhibit some specificity for feeding, perhaps via interactions with the striatal opioid system.
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Authors
Michelle L. Perry, Brian A. Baldo, Matthew E. Andrzejewski, Ann E. Kelley,