Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4315547 | Behavioural Brain Research | 2008 | 6 Pages |
Abstract
Sub-chronic phencyclidine (PCP) treatment mimics certain aspects of schizophrenia symptomology in rats. However, there is a marked lack of attempts to model negative symptomology such as social behaviour deficits in female rats. This study was conducted to assess whether sub-chronic PCP treatment produces social interaction deficits in female rats and to ascertain if these deficits can be reversed by either typical (haloperidol) or atypical (clozapine and ziprasidone) antipsychotics.
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Authors
Shikha Snigdha, Joanna C. Neill,