Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4315682 | Behavioural Brain Research | 2007 | 5 Pages |
Abstract
Experimental validation of cell replacement therapy as a treatment of neurodegenerative diseases requires the demonstration of graft-mediated behavioural recovery. The Corridor task proved to be simple and efficient to conduct with a robust ipsilateral retrieval bias in our rodent Huntington's disease model. The Corridor task is a viable behavioural option, particularly to non-specialised laboratories, for the evaluation of lateralised striatal damage and the probing of alternative therapeutic strategies, including transplantation.
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Authors
Máté D. Döbrössy, Stephen B. Dunnett,