Article ID Journal Published Year Pages File Type
4315758 Behavioural Brain Research 2007 4 Pages PDF
Abstract
Anxiety was assessed in rats treated with 5 mg/kg of PCP bid for 7 days. One week after withdrawal, measures were collected in the light/dark apparatus and during exposure to a cat odor. PCP decreased time spent in the lit area and number of contacts with a cat collar. PCP thus amplified rats' fear of unprotected environments and predatory threats, which seems compatible with the distorted emotional experience in human schizophrenia.
Related Topics
Life Sciences Neuroscience Behavioral Neuroscience
Authors
, , ,