Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4315758 | Behavioural Brain Research | 2007 | 4 Pages |
Abstract
Anxiety was assessed in rats treated with 5Â mg/kg of PCP bid for 7 days. One week after withdrawal, measures were collected in the light/dark apparatus and during exposure to a cat odor. PCP decreased time spent in the lit area and number of contacts with a cat collar. PCP thus amplified rats' fear of unprotected environments and predatory threats, which seems compatible with the distorted emotional experience in human schizophrenia.
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Authors
Marie-Claude Audet, Sonia Goulet, François Y. Doré,