Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4320119 | Brain Research Bulletin | 2007 | 4 Pages |
Abstract
To clarify the brain phenomena, to prove directly the major biochemical pathways in cerebral tissue, and to discover the crucial steps in brain pathology, it is necessary to develop a high speed deep-tissue imaging techniques with high spatial and temporal resolution, and ultra-fast and highly selective molecular sensors, giving a possibility to monitor target molecules directly in their physiological environment. This technical comment accents on the perspectives for development of direct approach for investigation of function/flow coupling phenomenon and zinc transport into the brain, based on the current progress in development of ultra-fast molecular sensors for direct visualization of biochemical mediators and neurotransmitters, and high speed multi-photon deep-tissue imaging.
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Authors
Rumiana Bakalova,