| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4320787 | Neuron | 2016 | 4 Pages |
Abstract
In this issue, Chandran et al. (2016) pursue a multi-level bioinformatics approach combined with wet bench validation to identify gene networks associated with the regenerative state of injured adult sensory neurons. A small molecular compound, ambroxol, mimics aspects of the identified gene expression patterns and promotes axon regeneration in the injured adult mouse CNS, demonstrating feasibility of in silico-based methods to identify compounds that promote neuronal growth following CNS injury.
Related Topics
Life Sciences
Neuroscience
Cellular and Molecular Neuroscience
Authors
Choya Yoon, Roman J. Giger,