Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4320974 | Neuron | 2014 | 5 Pages |
Abstract
Human genetics is a rational starting point for target identification in drug discovery, yet this approach has found little application in neuroscience. Recent large-scale analyses have begun to identify robust genetic loci for schizophrenia, providing an opportunity to derive novel drug targets. Here, we summarize a strategy for applying human genetics to neuroscience drug discovery.
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Authors
Christian R. Schubert, Hualin S. Xi, Jens R. Wendland, Patricio O’Donnell,