Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4322569 | Neuron | 2007 | 4 Pages |
Abstract
A key question in brain development is how migration of neuronal precursors is guided to establish the ordered laminar layers. In the April 20, 2007 issue of Cell, Guan et al. show that the leading process of migrating cerebellar granule neurons senses repulsive Slit molecules by generating a Ca2+ wave that propagates to the soma to cause reversal of cell polarity and migration.
Related Topics
Life Sciences
Neuroscience
Cellular and Molecular Neuroscience
Authors
Janet Alder, James Q. Zheng,