Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4322929 | Neuron | 2009 | 4 Pages |
Abstract
In addition to its role in glycolysis, GAPDH has been implicated as a mediator of neurotoxicity triggered by nitrosative stress. In this issue of Neuron, Sen et al. identify a novel, negative regulator of this GAPDH neurotoxic pathway termed GOSPEL, which, like GAPDH itself, is regulated by S-nitrosylation.
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Authors
Tomohiro Nakamura, Stuart A. Lipton,