Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4322931 | Neuron | 2009 | 4 Pages |
Abstract
Stretch reflex circuits are a prime example of wiring specificity in the vertebrate spinal cord. Homonymous sensory afferents and motoneurons typically form monosynaptic connections, while neurons innervating antagonistic or unrelated muscles do not. Pecho-Vrieseling et al. now show that the semaphorin Sema3E and its receptor Plexin-D1 prevent monosynaptic connectivity in the cutaneous maximus muscle stretch reflex circuit.
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Authors
Géraldine S. Maro, Kang Shen, Hwai-Jong Cheng,