| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4323018 | Neuron | 2006 | 4 Pages |
Abstract
L-type voltage-gated calcium channels (LTCs) may control neuronal gene expression by increasing nuclear Ca2+ levels or regulating Ca2+/calmodulin-dependent transcription factors. In the November 3 issue of Cell, Gomez-Ospina et al. demonstrate another signaling mechanism, in which a C-terminal fragment of LTC translocates to the nucleus in a calcium-dependent manner and directly regulates transcription.
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Authors
Hee Jung Chung, Lily Y. Jan,