Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4323128 | Neuron | 2008 | 4 Pages |
Abstract
The homeobox transcription factor, Nkx2-1, plays multiple roles during forebrain development. Using restricted genetic ablation of Nkx2-1, in this issue of Neuron, Butt et al. show that Nkx2-1 in telencephalic progenitors regulates interneuron subtype specification, while Nóbrega-Pereira et al. demonstrate that postmitotic Nkx2-1 regulates migration and sorting of interneurons to the striatum or cortex by controlling the expression of the guidance receptor, Neuropilin-2.
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Authors
Laura A.B. Elias, Gregory B. Potter, Arnold R. Kriegstein,