Article ID Journal Published Year Pages File Type
4323302 Neuron 2006 4 Pages PDF
Abstract

It has been a longstanding challenge for experimentalists to manipulate precisely the spatial and temporal patterns of synaptic input to the dendritic tree in order to mimic activity occurring in the intact brain and determine their importance for synaptic integration. In this issue of Neuron, Losonczy and Magee have used rapid multisite two-photon uncaging of glutamate to define patterns of synaptic input on a submillisecond and micron scale to investigate the rules for summation of synaptic inputs in the fine oblique dendrites of pyramidal neurons.

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Life Sciences Neuroscience Cellular and Molecular Neuroscience
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