| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4324742 | Brain Research | 2013 | 10 Pages |
Abstract
⺠BMP4 expression was down-regulated in glioblastoma compared to normal brain in human sample. ⺠BMP4 expression was down-regulated in human multidrug resistance cell line U251/TMZ compared to U251 cells. ⺠BMP4 reversed MDR of glioblastoma both in vitro and in vivo. ⺠BMP4 can negatively regulate BCL-2 and GDNF in glioblastoma; BCL-2 and GDNF can positively regulate MDR of glioblastoma. ⺠BMP4 reversed MDR by modulation of BCL-2 and GDNF in glioblastoma.
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Neuroscience (General)
Authors
Baohui Liu, Qianxue Chen, Daofeng Tian, Liquan Wu, Huimin Dong, Junmin Wang, Baowei Ji, Xiaonan Zhu, Qiang Cai, Long Wang, Shenqi Zhang,