Article ID Journal Published Year Pages File Type
4325004 Brain Research 2012 10 Pages PDF
Abstract
► pMCAO model is used to analyze sulindac's neuroprotective effect. ► Sulindac reduces the neurological deficits, infarct volumes and brain edema. ► Sulindac activates the impaired Wnt/β-catenin pathway in cerebral ischemia. ► Sulindac inhibits neuronal apoptosis in cerebral ischemia. ► Sulindac ameliorates the permeability of blood brain barrier in cerebral ischemia.
Related Topics
Life Sciences Neuroscience Neuroscience (General)
Authors
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