Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4325033 | Brain Research | 2012 | 9 Pages |
Abstract
⺠2MBG and 2MB accumulate in SBCAD deficiency. ⺠2MBG induces brain lipid oxidative damage. ⺠2MBG reduces nonenzymatic brain antioxidant defenses. ⺠2MBG-induced effects are possibly mediated by reactive oxygen species. ⺠Oxidative stress may contribute to the neuropathology found in SBCAD deficiency.
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Neuroscience
Neuroscience (General)
Authors
Lisiane Aurélio Knebel, Ãngela Zanatta, Anelise Miotti Tonin, Mateus Grings, Leonardo de Moura Alvorcem, Moacir Wajner, Guilhian Leipnitz,