| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4325146 | Brain Research | 2012 | 14 Pages |
Abstract
⺠Resveratrol consumption protects ovariectomized rats chronically treated with D-galactose from developing memory decline. ⺠Regulation of the redox status in serum and in hippocampus is one of the mechanisms. ⺠Long-term resveratrol consumption does not induce the effect on uterus compared with estrogen therapy. ⺠This study can provide evidence for the prevention by resveratrol from developing memory loss.
Keywords
T-SODOFRSERMMWMovariectomizedHRTOVXRESGSHTBARSGSSGD-galactoseGSH-PxROSEstradiolEstrogenEstrogen TherapyTemAlzheimer's diseaseOxidative stressstandard error of the meanOxygen-derived free radicalsResveratrolBlood–brain barrierBBBtotal superoxide dismutaseMorris water mazeSEMSelective estrogen receptor modulatorthiobarbituric acid reactive substancesTransmission electron microscopehormone replacement therapybody weightGlutathioneoxidized glutathioneglutathione peroxidaseReactive oxygen species
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Authors
Haifeng Zhao, Qiao Niu, Xuemin Li, Tiantian Liu, Yunan Xu, Hao Han, Wanrong Wang, Ningxiu Fan, Qinqin Tian, Huifeng Zhang, Zelan Wang,