Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4325168 | Brain Research | 2012 | 6 Pages |
Abstract
⺠Rat middle cerebral artery occlusion model is used to analyze celastrol's effect. ⺠Celastrol ameliorates neurological deficit, brain edema and infarct size. ⺠Celastrol downregulates expression of p-JNK, p-c-Jun and NF-κB. ⺠Celastrol has protective effect in the acute phase of cerebral ischemia.
Related Topics
Life Sciences
Neuroscience
Neuroscience (General)
Authors
Yanhua Li, Dan He, Xiangjian Zhang, Zongjie Liu, Xiaolin Zhang, Lipeng Dong, Yinxue Xing, ChaoHui Wang, Huimin Qiao, Chunhua Zhu, Yulin Chen,