| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4325413 | Brain Research | 2012 | 10 Pages |
Abstract
⺠Sigma 1 receptor compounds are neuroprotective for HT-22 hippocampal cells. ⺠Cytoprotection correlates with sigma 1, but not sigma 2, receptor affinity. ⺠Sigma 1 selective compounds were neuroprotective using a rodent model of stroke. ⺠Sigma 1 selective compounds represent a therapeutic strategy for treating stroke.
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Neuroscience
Neuroscience (General)
Authors
Robert R. Luedtke, Evelyn Perez, Shao-Hua Yang, Ran Liu, Suwanna Vangveravong, Zhude Tu, Robert H. Mach, James W. Simpkins,