Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4325499 | Brain Research | 2012 | 10 Pages |
Abstract
⺠gp120 could induce neuronal apoptosis and inhibit neurite outgrowth. ⺠Sigma-1 receptor agonist PPBP could attenuate neurotoxicity of gp120. ⺠The neurotoxicity of gp120 associated with low expression of bcl-2 and bax. ⺠Only low expression of bcl-2 induced by gp120 could be reversed by PPBP.
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Authors
Yulin Zhang, Ying Shi, Luxin Qiao, Yu Sun, Wei Ding, Honghai Zhang, Ning Li, Dexi Chen,