Article ID Journal Published Year Pages File Type
4325499 Brain Research 2012 10 Pages PDF
Abstract
► gp120 could induce neuronal apoptosis and inhibit neurite outgrowth. ► Sigma-1 receptor agonist PPBP could attenuate neurotoxicity of gp120. ► The neurotoxicity of gp120 associated with low expression of bcl-2 and bax. ► Only low expression of bcl-2 induced by gp120 could be reversed by PPBP.
Related Topics
Life Sciences Neuroscience Neuroscience (General)
Authors
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