Article ID Journal Published Year Pages File Type
4326227 Brain Research 2011 10 Pages PDF
Abstract
►6-OHDA induced lesions produce the alterations in the behavioral pattern and oxidative damage. ►Oxidative stress contributes to the cascade leading to dopaminergic cell degeneration. ►There is a loss of tyrosine hydroxylase positive staining in the striatum following intrastriatal 6-OHDA. ►Results suggest that curcumin protects against 6-OHDA induced neurodegeneration of nigrostriatal dopaminergic neuronal pathway.
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