| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4326279 | Brain Research | 2010 | 16 Pages |
Abstract
âºCell proliferative ability of rhEpo appears to be greater than that of simvastatin. âºSimvastatin is more effective than rhEpo in repairing damaged axons after TBI. âºSpatial learning is better correlated with cortical axonal profile. âºMemory is better correlated with hippocampal axonal profile. âºCombined effects of rhEpo and simvastatin after TBI are stronger than either alone.
Keywords
TBIMIP-2NFkBHCTeNOSMWMTLR-4EpoREPOICAM-1TNF-alphaY mazeCREBJAK2IL-1betaIL-6STAT-3CCIBDNFTraumatic brain injuryAxonal injuryAkt/PKBPosttraumatic stress disorderPTSDerythropoietinRecombinant human erythropoietinendothelial nitric oxideinterleukin-6interleukin-1betaBrdUbromodeoxyuridinelong-term potentiationLTPtumor necrosis factor-alphaCell proliferationMemoryCNSrhEPOblood brain barrierBBBcentral nervous systemdentate gyrusBrain-derived neurotrophic factornuclear factor kappa BCortexMorris water mazesignal transducer and activator of transcription 3intercellular adhesion molecule-1hematocritcontrolled cortical impactErythropoietin ReceptorToll-like receptor 4Spatial learning
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Authors
Neelima B. Chauhan, Rodolfo Gatto,