| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4326414 | Brain Research | 2010 | 11 Pages |
Abstract
⺠SP600125 has a protective effect on hippocampal neurons in amygdala kindled rats by inhibiting JNK activation. ⺠JNK phosphorylation is involved in the process of hippocampal sclerosis in amygdala kindled rats. ⺠The amygdala kindling epilepsy model resembles the human temporal lobe epilepsy. ⺠JNK pathway may be a new target to interfere with the development of hippocampal sclerosis in the temporal lobe epilepsy.
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Authors
Xu Chen, Jun Wu, Dong Hua, Kai Shu, Jian-Zhi Wang, Ling Li, Ting Lei,