| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4332546 | Brain Research | 2006 | 6 Pages |
Abstract
Preliminary investigations, studying gene expression and biochemical activities of enzymes d-amino acid oxidase (DAAO) and kynurenine aminotransferase-1 (KAT-1), revealed elevated cerebellar KAT-1 and DAAO activities in post-mortem brain samples from schizophrenic versus normal individuals. In addition, we have identified a transcript of DAAO, which was expressed in significantly higher quantities in the diseased cerebellum but not detected in the parietal cortex where DAAO activity is absent.
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Authors
Ranjna Kapoor, Kelly SY Lim, Alice Cheng, Therese Garrick, Vimal Kapoor,