Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4332860 | Brain Research | 2006 | 6 Pages |
Abstract
Adrenaline is a potent respiratory regulator. However, adrenergic contribution to the developing respiratory center has not been studied extensively. Adrenaline application on embryonic day 17 medulla-spinal cord block preparations abolished non-respiratory activity and enhanced respiratory frequency. Phentolamine application on neonatal blocks that produced stable neonatal respiration resulted in respiratory destabilization. These results suggest that central adrenergic modulation is involved in fetal respiratory development and maintenance of stable respiration.
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Authors
Morimitsu Fujii, Kazuo Umezawa, Akiko Arata,