| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4333525 | Brain Research | 2006 | 5 Pages |
Abstract
γ-Aminobutyric acid (GABA) is inhibitory in adult, but excitatory in neonatal, neurons. The switch from excitatory to inhibitory action is due to a negative shift in the equilibrium potential for the GABAA receptor-mediated postsynaptic current (EGABA-PSC). Here, we report that, in neonatal rat hippocampal CA1 neurons, presynaptic theta-burst activation induces not only a shift in EGABA-PSC towards that in adult neurons, but also a recruitment of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA)-receptor-mediated postsynaptic currents.
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Authors
M. Ouardouz, J.-Y. Xu, B.R. Sastry,