Article ID Journal Published Year Pages File Type
4333619 Brain Research Reviews 2011 7 Pages PDF
Abstract

The concepts underlying the connectivity of neurons and the dynamics of interaction required to explain information processing have undergone significant change over the past century. A re-examination of the evolution of the modern view in historical context reveals that rules for connectivity have changed in a manner that might be expected from critical analysis enabled by technical advance. A retrospective examination of some germane issues that moved Camillo Golgi to question the widely held dogma of his era reveals network principles that could not have been recognized a century ago. The currently evolving rules of cellular discontinuity and interaction have proven sufficiently complex to justify the arguments of critical skepticism that sustain scientific progress.

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